Endocrine Abstracts

Introduction: Primary hyperparathyroidism is associated with multiple complications: severe bone disease is one of them. Osteomalacia is by definition a metabolic bone disease characterized by a softening of the bones. We herein report a rare case of an association between primary hyperparathyroidism with osteitis fibrosa cystica and osteomalacia caused by a severe vitamin D deficiency.Observation: A 37-year old woman was referred for investigation of we...

Introduction: Sleep is essential for the proper functioning and the well-being of the body. Poor sleep quality has many negative effects on the patient health. The aim of our study was to determine the prevalence of sleep disorders in patients with type 2 diabetes and to identify the associated factors.Methods: It is a cross-sectional study including 51 patients and conducted in the nutrition department A of the institute of nutrition of Tunis. The patie...

Introduction: Wilson’s disease is a rare and serious genetic disorder. The accumulation of copper in glands causes several endocrine pathologies. Herein, we report a rare case of hypophysitis with corticotropic deficiency caused by Wilson’s disease.Observation: A 33-years-old female patient was referred to the endocrinology department for hypoglycemia. She had a history of Wilson’s disease diagnosed at the age of nine complicated by cirrho...

Introduction: Isolated hypogonadotropic hypogonadism is a heterogeneous group of genetic abnormalities affecting the hypothalamic pituitary gonadal axis. The main mechanism consists of an impairment of the production or the action of gonadotropin releasing hormone (GnRH). While several mutations have been identified, the majority of cases remain without etiology. The objective of our study was to describe the clinical and biological profiles of these diseases.<p class="abs...

Introduction: Thyroid eye disease (TED) is an autoimmune inflammatory disorder affecting the orbital tissues. It occurs with thyroid dysfunction notably Graves’ disease. TED exhibits different severity patterns and has a lot of risk factors. We, herein, report a rare case of a severe TED developing after COVID-19 infection in a patient initially treated for hyperthyroidism without ocular manifestations.Observation: A 48-year-old female with a histor...

Introduction: Graves disease is a frequent etiology of hyperthyroidism. It is defined as a diffuse hyperfunctioning of the thyroid gland caused by an autoimmune disorder. We herein present a rare case of unilateral Graves disease involving the right lobe of the thyroid.Observation: A 44-year-old woman was referred for investigation of subclinical hyperthyroidism revealed by a routine check-up. On physical examination, she had tremor, eyelid retraction, t...